Call for Papers - Special Issue on Air Pollution and Brain Health
摘要截稿:
全文截稿: 2019-09-01
影响因子: 3.881
期刊难度:
CCF分类: 无
中科院JCR分区:
• 大类 : 医学 - 3区
• 小类 : 生化与分子生物学 - 3区
• 小类 : 神经科学 - 3区
Overview
There is growing international recognition of air pollution as a major contributor to impaired brain health and neurological dysfunction. Ambient air pollution is a complex mixture of particulate matter (PM), gases, organic compounds and metals. Particles derived from industrial or automotive sources such as tire wear comprise the main sources of pollutant exposure for the general population. In addition, high levels of transition metals are generated by electrical public transport systems, which contribute to the PM exposure in urban areas. Further sources include wood fires and use of biomass fuels for heating and cooking. Air pollution is a known risk factor for stroke and vascular disease, and is also associated with exacerbated cognitive dysfunction. Imaging studies have reported metabolic and structural brain alterations in individuals exposed to air pollution. While some of the actions of air pollution on brain health may be attributes to increased inflammation and oxidative stress, there remains little understanding of the molecular basis of air pollution damage in the brain. Epidemiological studies have also identified a potentially critical association between air pollution and dementia (including Alzheimer’s disease (AD), which currently affects 47 million people worldwide). Recent evidence shows that exposure to air pollutants is associated with an increased risk of AD and causes pathological changes in the brain. People who live in areas of high air pollution have a substantially increased risk of developing dementia although the specific pollutant(s) associated with increased dementia risk have not been identified. With increased urbanization and aging of the human population, understanding the role of air pollution in brain health has taken on a new sense of urgency. This special issue has been planned to help bring a greater understanding of air pollution and its role in brain health to the neuroscience research community and accelerate new initiatives for investigation of this major health issue.
To help facilitate international collaboration in research on air pollution and brain health, this special issue will also feature selected articles from members of the APOLLO consortium: ‘The Polluted Brain: Interaction of Air Pollution with Alzheimer’s disease’, an association of international researchers with a major interest in this leading brain health issue. We hope that many other researchers in this field will contribute to this special issue to help share the latest findings and promote development of new research directions and collaborations.