Metabolism, Cognition, and the Brain Throughout Life
• 大类 : 医学 - 2区
• 小类 : 神经科学 - 2区
Metabolism is defined as the chemical and physical processes by which an organism utilizes fuel for energy and growth. Classically, metabolism is divided into the breakdown of fuel for energy, known as catabolism, and the creation of new cellular components, known as anabolism. Well described catabolic pathways, such as glycolysis, and anabolic pathways, such as building proteins from amino acids, have been well studied in the context of health and disease. In the last decade, there has been mounting interest in understanding how changes in metabolic function leads to increased disease risk, including diseases of the nervous system.
The goal of this special edition of Neurobiology of Disease is to better understand the connection between the individual and collective components of the Metabolic Syndrome and a wide array of neurological disorders that span the lifetime of patients, from autism spectrum disorder and neurodevelopmental disorders in youth, to chronic progressive neurodegenerative disorders in adults.
The Special Issue will include authoritative state of the art review articles on:
- Epigenetics and brain outcomes: Generational changes - Jennifer Tuscher and Jeremy Day
- Metabolic interventions that can result in improved outcomes in children with developmental disorders (autism) - Susana Mierau and Ann Neumeyer
- Diabetes: Cognition changes throughout the lifespan - Eelco van Duinkerken and Christopher Ryan
- Obesity and cognition- Catrina Sims-Robinson and Eva Feldman
- Metabolic interventions that improve cognition in neurodegenerative disorders – Tony Hannan
- Protecting the aging brain via improved metabolic function - Devin Wahl and David Le Couteur