Call for papers on the special issue: RNA Structural Challenges, Modeling, and Design
• 大类 : 生物 - 3区
• 小类 : 生化与分子生物学 - 3区
• 小类 : 生物物理 - 3区
• 小类 : 细胞生物学 - 4区
The heightened appreciation for the central role of RNA molecules in all cellular processes — from catalysis to control of gene expression to cellular differentiation — combined with the practical applications of synthetic RNAs in biomedicine and biomolecular engineering has raised new challenges regarding RNA structure analysis, prediction, and design to both experimental and theoretical scientists. These challenges have produced many innovative approaches, including interdisciplinary efforts, to analyze, predict, simulate, and design RNA molecules. While many successes have been reported, progress in the field has been hampered by limited experimental resolution and an incomplete understanding of RNA tertiary structure, especially for large RNAs. Though RNA structure is believed to be hierarchical, the difficult problem of understanding and predicting its tertiary structure from its primary, as well as secondary, structure remains unsolved in general.
We welcome contributions from scientists working to advance the field on both the genomic and molecular levels of RNA using novel experimental, mathematical, statistical, and computational approaches.
Submit your original research or review paper in this area to be included in this dedicated issue, to be guest edited by François Major, Tamar Schlick and Anna Pyle. All papers will be published online as soon as they are redacted and will be fully citable.