The International Symposium on High-Performance Computer Architecture provides a high-quality forum for scientists and engineers to present their latest research findings in this rapidly-changing field. Authors are invited to submit papers on all aspects of high-performance computer architecture. Topics of interest include, but are not limited to: -Processor, cache, and memory architectures -Parallel computer architectures -Multicore and multiprocessor architectures -Impact of technology on architecture -Dependable/secure architectures -High-performance I/O systems -Embedded, reconfigurable, and heterogeneous architectures -Interconnect and network interface architectures -Architectures for cloud-based HPC and data centers -Innovative hardware/software trade-offs -Impact of compilers and system software on architecture -Performance modeling and evaluation -Architecture for novel application workloads, such as AI or graph analytics -Architectures for emerging technology and applications